منابع مشابه
Assessing dry powder inhalers
To enable what would otherwise be impractical, invasive and potentially dangerous testing, and to remove the huge variation and costs associated with human subjects, it is common practice to test inhalation devices and formulations using in vitro test apparatus. Industry standard test conditions and relevant parameters have been devised and published by the regulatory authorities and within the...
متن کاملDry powder inhaler formulation.
A drug product combines pharmacologic activity with pharmaceutical properties. Desirable performance characteristics are physical and chemical stability, ease of processing, accurate and reproducible delivery to the target organ, and availability at the site of action. For the dry powder inhaler (DPI), these goals can be met with a suitable powder formulation, an efficient metering system, and ...
متن کاملFormoterol dry powder in asthma.
We read with interest the paper by Douglas and coworkers (July 1993;48,719-21) on the possible inheritance of sleep disturbed breathing. Investigating 40 first degree relatives of patients with sleep apnoeas, they found a high prevalence of sleep apnoeas/ hypopnoeas (25%), several times higher than the prevalence in a random sample of the British population (5%).' The authors concluded that a f...
متن کاملDry powder inhalers: an overview.
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly in Europe, where they currently are used by a large number of patients for the delivery of medications to treat asthma and chronic obstructive pulmonary disease. The acceptance of DPIs in the United States after the slow uptake following the introduction of the Serevent Diskus in the late 1990s has been ...
متن کاملDry Powder Inhalers: A Review
In the recent years pulmonary drug delivery system is found to be preferred route of administration for various drugs. It has been divided into 3 classes: Nebulizers, pMDI, DPI.DPI are used as an alternative to pMDI because pMDI contains propellant (CFC) which has ozone depletion characteristics. DPI delivers medication in the form of dry powder to lungs. DPI is formulated either as a carrier b...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1886
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(02)13298-3